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Hyperglycaemia in criticaly ill patients

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Abstract


The review highlights the problem of stress-induced hyperglycaemia (IT). The study of this condition is in demand because there is an association between IT and increasing number of complications and mortality among patients in critical state. In the review pathological and physiological mechanisms of stress-induced IT syndrome and its components are shown. These are acute IT, insulin resistance and hyperinsulinemia. The range of critical states, in which development of stress-induced IT is more probable and the IT negative impact on different organs and systems are described in the article.
Clinical significance, influence on treatment and complications development of stress-induced IT are considered. It has been shown that adequate control and correction of IT are leading to improvement in critically ill patients state. Much attention in the review is paid to early diagnostics of any carbohydrate abnormalities in critical care medicine, as well as to prevention and optimal correction of IT. The variety of IT correction methods, target glucose levels and various therapeutic methods of hyperglycaemia correction are discussed. Dealing with hyperglycaemia in intensive care units is described in details.

Tatiana Valer'evna Klypa

Clinical Hospital №119, Moscow

Author for correspondence.
Email: klypa@hotbox.ru

Russian Federation MD, PhD, The head of Anesthesiology and ICU department

Maria Sergeevna Orehova

Clinical Hospital №119, Moscow

Email: mysterylife@rambler.ru

Russian Federation

MD, Anesthesiology and ICU department

Ludmila Ivanovna Zabrosaeva

Smolensk State Medical Academy, Smolensk

Email: askold@list.ru

Russian Federation

MD, PhD, associate professor, Biochemistry chair

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  • Tarasova IA, Shestakov AL, Nikoda VV. Post-operative insulin resistance. Diabetes mellitus. 2017;20(2):119. doi: 10.14341/7637
  • Alekseenko OV, Risev AV, Luft VM, Kostenko VA, Kovalchuk EY. Nutritive correction of insulin resistance and hyperglycemia in acute myocardial infarction. HERALD of North-Western State Medical University named after I.I. Mechnikov. 2018;10(1):20. doi: 10.17816/mechnikov201810120-26

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Copyright (c) 2015 Klypa T.V., Orehova M.S., Zabrosaeva L.I.

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