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Diagnostic value of blood lipids testing in patients with high-normal and subclinical levels of TSH in prevention and treatment of dislipoproteinemia

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Abstract


The purpose of the study is to evaluate character of lipid profile changes in Novosibirsk populational sample of men and women (45–69 years) with subclinical and high-normal TSH levels. Current study was performed within the HAPIEE project “Determinants of cardiovascular diseases in Eastern Europe” of the Welcome Trust fond. Populational subsample of 280 subjects (125 men (44.6%) and 155 women (55.4%)) was analyzed. Received data showed that high-normal TSH levels within 1.71–4.05 mIU/l have been associated with higher levels of triglycerides, total cholesterol and LDL cholesterol, compared with low-normal TSH levels 0.17–0.47 mIU/l (р<0.05). Women with subclinical hypothyroidism had significantly higher average levels of total cholesterol and LDL cholesterol compared with women without thyroid disorders.

Email: rootnii@online.nsk.su
doktor med. nauk, starshiy nauchnyy sotrudnik laboratorii kliniko-populyatsionnykh i profi- lakticheskikh issledovaniy terapevticheskikh i endokrinnykh zabolevaniy NII terapii SO RAMN

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