Thyrotoxic crisis. Rare manifestations and the difficulties of timely diagnostics

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Thyroid storm is a rare, life-threatening complication of thyrotoxicosis. It may be precipitated by an acute event such as discontinuation of antithyroid drug therapy, thyroid or nonthyroidal surgery, infection, parturition, or an acute iodine load. The variety of clinical presentations of this disorder can lead to delayed diagnostics and high mortality.

The typical and atypical clinical manifestations, diagnosis, and management of thyroid storm will be reviewed here. It also describes a case study of a young man with thyroid storm.

About the authors

Olegovna Dar'ya Gazizova

Burnasyan Federal Medical Biophysical Center, Moscow

Author for correspondence.

Russian Federation MD, PhD, endocrinologist

Sergey Viktorovich Vasichkin

Burnasyan Federal Medical Biophysical Center, Moscow


Russian Federation MD, neurologist

Pavel Olegovich Kharkenen

Burnasyan Federal Medical Biophysical Center, Moscow


Russian Federation Head of the neuroreanimation department

Dmitriy Kirillovich Fomin

Russian Scientific Center of Roentgeno-Radiology, Moscow


Russian Federation MD, PhD, Head of the nuclear medicine clinic

Lyubov' Petrovna Chupina

Burnasyan Federal Medical Biophysical Center, Moscow


Russian Federation MD, PhD, neurologist

Anzhela Borisovna Kozhokaru

Burnasyan Federal Medical Biophysical Center, Moscow


Russian Federation MD, PhD, neurologist

Natal'ya Sergeevna Shevchenko

Burnasyan Federal Medical Biophysical Center, Moscow


Russian Federation MD, Head of the neurology department


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Copyright (c) 2015 Gazizova O.D., Vasichkin S.V., Kharkenen P.O., Fomin D.K., Chupina L.P., Kozhokaru A.B., Shevchenko N.S.

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