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Features of eating behavior, emotional state and metabolic parameters in obese patients with insomnia

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Abstract


Aim. The aim of this study was to investigate the influence of insomnia on eating behavior, anxiety, depression, metabolic and hormonal parameters in obese patients. Materials and Methods. The study involved 104 patients with primary obesity from 20 to 55 years old: 47 men and 57 women, mean age 39 years, mean body weight 118 kg, BMI 39.6. Patients were divided into 2 groups: the first group consisted of patients with complaints of insomnia (n=45), the second (control) group (n=59) were patients without sleep disorders. Results. Mean levels of anxiety and depression were significantly higher in the first group. The results of research showed a statistically significant association emotional eating and insomnia. Patients with chronic insomnia without obstructive sleep apnea had low levels of free cortisol in 24-hour urinary compared with patients without sleep disorders (169 [145, 194] vs. 324 [244, 330], respectively, p=0.001), positive correlation with total sleep time, sleep efficiency, and negative with wake time during sleep period time. Conclusions. Sleep disorders in obese patients are one of the factors contributing to the increase in food intake in response to changes in emotional state on the background of "hidden" anxiety and depressive disorders. It is possible that the data eating disorders and psychological status may have a negative impact on the dynamics of weight during the treatment of obesity.

Email: nstr84@mail.ru
Endocrinology Research Centre

Email: polouekt@mail.ru
I.M. Sechenov's First Moscow State Medical University

Email: slv63@mail.ru
Endocrinology Research Centre

Email: melnich@endocrincentr.ru
Endocrinology Research Centre

Endocrinology Research Centre

Email: goncharov@endocrincentr.ru
Endocrinology Research Centre

  1. Вознесенская Т.Г. Типология нарушений пищевого поведения и эмоционально-личностные расстройства при ожирении и их коррекция / В кн.: Ожирение под ред. Дедова И.И., Мельниченко Г.А. М., МИА. 2004: 234-71.
  2. Волкова Г.Е., Романцова Т.И., Вознесенская Т.Г., Роик О.В. Пищевое поведение у пациентов с ожирением. Ожирение и метаболизм. 2007 (2):17-21.
  3. Гурова О.Ю., Бобров А.Е., Романцова Т.И., Роик О.В. Метаболические и психопатологические особенности у у больных с морбидным ожирением. Ожирение и метаболизм. 2007.;3:28-32.
  4. Полуэктов М.Г. Первичные и вторичные инсомнии и расстройства дыхания во сне. Журнал неврологии и психиатрии. 2011; 9 (2):10-18.
  5. Полуэктов М.Г. Эндокринная система и нарушения сна. / В кн.: Под ред. Левин Я.И. Полкуэктов М.Г. Сомнология и медицина сна. М.: Медфорум, 2013: 408-422.
  6. Протокол исследования больных с нарушениями сна. [Электронный ресурс]. URL: http//www.sleepmed.ru.
  7. Рекомендации Российской ассоциации эндокринологов. Диагностика и лечение ожирения у взрослых. Под ред. Дедова И.И. 2010,12 стр.
  8. American Academy of Sleep Medicine. International classification of sleep disorders, 2 nd ed.: Diagnostic and coding manual. Westchester, Ill.: American Academy of Sleep Medicine, 2005.
  9. Brumpton B, Langhammer A, Romundstad P, Chen Y and Mai X-M The associations of anxiety and depression symptoms with weight change and incident obesity: The HUNT Study. Int J Obes (Lond). 2012. URL: http://www.ncbi.nlm.nih.gov/pubmed/23229732.
  10. Cappuccio FP, Taggart FM, Kandala NB et el. Meta-Analysis of Short Sleep Duration and Obesity in Children and Adults. Sleep. 2008; 31(5): 619-626.
  11. Hach I, Ruhl UE, Klotsche J, Klose M, Jacobi F. Associations between waist circumference and depressive disorders. J Affect Disord. 2006 Jun;92(2-3):305-8. Epub 2006 Feb 28.
  12. Hasler, G., Buysse, D.J., Klaghofer, R., Gamma, A., Ajdacic, V., Eich, D., Rossler, W., Angst, J., The association between short sleep duration and obesity in young adults: a 13-year prospective study. Sleep. 2004;27 (4):661-666.
  13. Janson, C., Lindberg, E., Gislason, T., Elmasry, A., Boman, G. Insomnia in men - a 10-year prospective population based study. 2001, Sleep 24 (4), 425-430.
  14. Killick R, Banks S, Liu PY. Implications of sleep restriction and recovery on metabolic outcomes. J Clin Endocrinol Metab. 2012;97(11):3876-90.
  15. Morselli L., Leproult R., Balbo M., Spiegel K. Role of sleep duration in the regulation of glucose metabolism and appetite Clin Endocrinol Metab. 2010;24(5): 687-702.
  16. Motivala SJ, Tomiyama AJ, Ziegler M, Khandrika S, Irwin MR. Nocturnal levels of ghrelin and leptin and sleep in chronic insomnia. Psychoneuroendocrinology. 2009;34(4):540-5.
  17. Nedeltcheva AV, Kessler L, Imperial J, Penev PD. Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin resistance and reduced glucose tolerance. J Clin Endocrinol Metab. 2009;94(9):3242-50.
  18. Rechtschaffen A, Kales A, editors. Los Angeles: Brain Information Service/Brain Research Institute, University of California; 1968. A manual of standardized terminology, techniques and scoring system of sleep stages in human subjects.
  19. Scheer FA, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci U S A. 2009;106:4453-8.
  20. Sharma S, Kavuru M. Sleep and Metabolism: An Overview. International Journal of Endocrinology. 2010. URL: http://www.hindawi.com/journals/ije/2010/270832/.
  21. Stunkard AJ, Messick S. The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J Psychosom Res 1985;29:71-83.
  22. Tsigos C, Chrousos GP Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress. J Psychosom Res 2002;53:865-871.
  23. Van Liempt S. Sleep disturbances and PTSD: a perpetual circle? Eur J Psychotraumatol. 2012 (3). http://www.ncbi.nlm.nih.gov/pubmed.
  24. Van Strien T, Frijters JER, Bergers GPA, Defares PB. The Dutch Eating Behavior Questionnaire (DEBQ) for assessment of restrained, emotional, and external eating behavior. Int J Eat Disord 1986;5:295-315.
  25. Vgontzas AN, Mastorakos G, Bixler EO, Kales A, Gold PW, Chrousos GP. Sleep deprivation effects on the activity of the hypothalamic-pituitary-adrenal and growth axes: potential clinical implications. Clin Endocrinol (Oxf). 1999 Aug;51(2):205-15.
  26. Vgontzas AN, Bixler EO, Lin HM, Prolo P, Mastorakos G, Vela-Bueno A, Kales A, Chrousos GP. Chronic insomnia is associated with nyctohemeral activation of the hypothalamic-pituitary-adrenal axis: clinical implications. J Clin Endocrinol Metab. 2001;86:3787-3794.
  27. Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Follet H, Kales A, et al. Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines. JCME. 2004;89:2119-2126.
  28. Zhao G, Ford ES, Dhingra S, Li C, Strine TW, Mokdad AH. Depression and anxiety among US adults: associations with body mass index. Int J Obes (Lond). 2009;33(2):257-66.

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Copyright (c) 2014 Strueva N.V., Poluektov M.G., Saveleva L.V., Melnithenko G.A., Katsya G.V., Goncharov N.P.

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