Evaluation of the hemostatic state, carbohydrate and lipid metabolism in young women with abdominal obesity and hypertension

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Aim of this study was to determine the characteristics of the laboratory parameters of hemostasis, carbohydrate and lipid metabolism in women with metabolic syndrome, isolated abdominal obesity or with hypertension.

Materials and methods. The study included 71 women aged 30 – 44 years and was conducted at laboratory study of hemostasis system, carbohydrate and lipid metabolism.

Results. In women with abdominal obesity and arterial hypertension we found an increased levels of glucose, total cholesterol, LDL-C and triglycerides and a decrease in a concentration of HDL-C compared to healthy women. The study of hemostasis revealed prothrombotic changes in the form of activation of coagulation hemostasis and fibrinolysis system activity.

Conclusions. The disorders of carbohydrate and lipid metabolism are very prevalent in young women with abdominal obesity and hypertension with every second woman meeting the criteria for the metabolic syndrome. The most pronounced signs of activation of blood coagulation markes was seen in women with abdominal obesity and hypertension. In women with the individual components of the metabolic syndrome there were no significant changes in carbohydrate and lipid metabolism, although we saw an early signs of activation of hemocoagulation.

About the authors

Veronika Andreevna Sumerkina

South Ural State Medical University

Author for correspondence.
Email: veronika.sumerkina@mail.ru

Russian Federation PhD, senior researcher at the Central Research Laboratory

Vasiliy Sergeevich Chulkov

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation PhD, Associate Professor at the Department of Faculty Therapy

Vladislav Sergeevich Chulkov

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation Assistant  at the Department of Faculty Therapy

Elena Stanislavovna Golovneva

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation MD PhD, professor of Normal Physiology Department

Larisa Fedorovna Telesheva

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation MD PhD, Professor of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics Department

Elena Anatol'evna Mezentseva

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation PhD, Senior Lecturer of Microbiology, Virology, Immunology and Clinical Laboratory Diagnostics Department

Karina Viktorovna Nikushkina

South Ural State Medical University

Email: kanc@chelsma.ru

Russian Federation PhD, a leading researcher at the  ImmunologyInstitute


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Copyright (c) 2015 Сумеркина В.А., Чулков В.С., Чулков В.С., Головнева Е.С., Телешева Л.Ф., Мезенцева Е.А., Никушкина К.В.

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