Treatment of intraoperative nasal cerebrospinal fluid leak of patients with hormone active pituitary adenomas

Cover Page


Intraoperative nasal cerebrospinal fluid leak are common during the transnasal transsphenoidal interven tions. In certain cases, it is a feature of these interventions. However, its amplification needs a mandatory treatment. In this article, we describe the technique for closure dural defects that have developed during the transnasal removal of hormone active pituitary adenomas, using thrombin and fibrinogen containing colla genic sponge.

About the authors

A Yu Grigoriev

doktor med. nauk, professor, zav. otdeleniem neyrokhirurgii FGBU ENTs

V N Azizyan

kand. med. nauk, st. nauch. sotr. otdeleniya neyrokhirurgii FGBU ENTs

O V Ivashenko

nauch. sotr. otdeleniya neyro khirurgii FGBU ENTs.


  1. Капитанов ДН, Лопатин АС, Потапов АА. Эндоскопическая диагностика и лечение назальной ликвореи. электронная статья, 2002 г.
  2. Коновалов АН, Лихтерман ЛБ, Потапов АА. Черепно-мозговая травма: Клиническое руководство. 1998.
  3. Охлопков ВА. Длительная посттравматическая базальная ликворея (клиника, диагностика, лечение, катамнез): дисс. ... канд. мед. наук. М., 1996.
  4. Потапов АА, Охлопков ВА, Лихтерман ЛБ, Кравчук АД. Посттравматическая базальная ликворея. М., 1997.
  5. Cusimano MD, Sekhar LN. Pseudocerebrospinal fluid rhinorrhea. J Neurosurgery. 1994;80:26-30.
  6. Nutkiewicz A, DeFeo DR, Kohout R et al. Cerebrospinal fluid rhinorrhea as a presentation of pituitary adenoma. J Neuro surgery. 1980;6:195-197.



Abstract - 1692

PDF (Russian) - 676



Copyright (c) 2013 ., ., .

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies