Diagnosis of medullary thyroid cancer and prognostic factors of disease aggressiveness

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Abstract


In the study were enrolled 137 patients with medullary thyroid cancer (MTC). Low 35%-sensitivity of FNAC and high accuracy of basal calcitonin in MTC diagnostics were found. Mutation analysis of the RET pro- tooncogene in familial and sporadic MTC, RAS -gene in sporadic MTC were done. The correlation between type of the mutation and disease aggressiveness was found.

About the authors

D O Gazizova

aspirant FGBU ENTs

D G Beltsevich

Email: beltsevich@rambler.ru
doktor med. nauk, gl. nauch. sotr. otd. khirurgii FGBU ENTs

A N Tiulpakov

doktor med. nauk, zav. otdeleniem nasledstvennykh endokrinopatiy FGBU ENTs

T V Soldatova

kand. med. nauk, zav. otdeleniem ul'trazvukovoy diagnostiki FGBU ENTs

A V Ilyin

zav. otdeleniem klinicheskoy biokhimii FGBU ENTs

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